CAS No.: 174671-46-6 | Tavaborole
Name: Tavaborole CAS No.: 174671-46-6 MDL No.:MFCD10699483 MF: C7H6BFO2 MW: 151.93 MP: 120-122℃ BP: 230.8±50.0 °C Density: 1.28±0.1 g/cm3 Purity: 95% Min. Appearance: White to beige powder
Categories:
Pharmaceutical Intermediates
Email:sale06@alfachem.cn
Product introduction
Name: Tavaborole
Synonyms:
5-Fluorobenzo[c][1,2]oxaborol-1(3H)-ol.
CAS No.: 174671-46-6
MDL No.:MFCD10699483
MF: C7H6BFO2
MW: 151.93
MP: 120-122℃
BP: 230.8±50.0 °C
Density: 1.28±0.1 g/cm3
Purity: 95% Min.
Appearance: White to beige powder
Application: Raw materials; Pharmaceutical raw material
Storage Condition: Sealed in dry, Store in freezer, under -20°C.

Synthesis Route (Yield 60%)

845301-93-1 174671-46-6
Stage #1: With n-butyllithium In tetrahydrofuran; hexanes at -78℃; for 0.83 h;
Stage #2: With Triisopropyl borate In tetrahydrofuran; hexanes at 20℃; for 1.75 h;
Stage #3: With hydrogenchloride In tetrahydrofuran; hexanes; water at 30℃;
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